個人簡歷

Education/Training:

• Ph.D. in School of Nutrition and Health Sciences, Taipei Medical University
• M.S. in School of Nutrition and Health Sciences, Taipei Medical University
• B.S. in School of Nutrition and Health Sciences, Taipei Medical University

Professional and Research Experience:

• 2023.08-present: Chair, School of Food Safety, College of Nutrition, Taipei Medical University
• 2023.08-present: Director, Master Program in Food Safety, College of Nutrition, Taipei Medical University
• 2021.08-present: Associate Professor, Master Program in Food Safety, College of Nutrition, Taipei Medical University

Awards and Honors:

• 2024: Second Prize, Excellent Research Paper Award, Teacher and Student Joint Academic Research Symposium, Taipei Medical University

Selected Publications:

1. Hou YC, Wu JM, Chen KY, Wu MH, Yang PJ, Lee PC, Chen PD, Sung-Ling Yeh SL, Lin MT. Glutamine and leucine administration attenuates muscle atrophy in sepsis. Life Sci., 2023, 314:121327.
2. Hou YC, Pai MH, Wu JM, Yang PJ, Lee PC, Chen KY, Yeh SL, Lin MT. Protective Effects of Glutamine and Leucine Supplementation on Sepsis-Induced Skeletal Muscle Injuries. Int. J. Mol. Sci., 2021, 22(23):13003.
3. Chen YC, Pai MH, Chen YT, Hou YC*. Dietary exposure to chlorpyrifos affects systemic and hepatic immune-cell phenotypes in diabetic mice. Toxicology, 2021, 452:152698. (*Corresponding author)
4. Huang HM, Pai MH, Yeh SL, Hou YC*. Dietary exposure to chlorpyrifos inhibits the polarization of regulatory T cells in C57BL/6 mice with dextran sulfate sodium-induced colitis. Arch. Toxicol., 2020, 94(1):141-150. (*Corresponding author)
5. Huang HM, Pai MH, Liu JJ, Yeh SL, Hou YC*. Effects of dietary exposure to chlorpyrifos on immune cell populations and inflammatory responses in mice with dextran sulfate sodium-induced colitis. Food Chem. Toxicol., 2019, 131:110596. (*Corresponding author)

Abstract

Chinese Title:

農藥暴露對於發炎之影響

English Title:

Effects of Pesticide Exposure on Inflammation

Abstract

Pesticides are indispensable resources for plant protection; however, improper use of pesticides can affect the safety of agricultural products and environmental ecology, and may also pose risks to human health. To monitor the safe use of pesticides, an acceptable daily intake (ADI) for each pesticide is generally established, along with an estimated daily intake, to evaluate potential health risks to humans. The ADI value is typically based on the no observed adverse effect level (NOAEL) from animal studies. However, recent studies have indicated that some pesticides can exert negative effects on unintended targets even at doses equal to or lower than the NOAEL. This presentation will focus on two insecticides—chlorpyrifos and cypermethrin, illustrating the adverse effects on inflammation, following dietary exposure to pesticides at NOAEL doses in animal studies.